ABSTRACT
Thepresentreviewaimstoassesstheblooddonationsafetybypeoplesufferedfromdiabetes,hypertension,malariaandcancer.Diabetes,hypertension,malariaandcancerhavebecomecommonhealthproblemsinhumansociety.Casesofbloodtransfusion-transmittedmalaria,hypertension,cancerandthesafetyofblooddonationbydiabeticpeoplehavebeendescribedaroundtheworldandhighlightedinsomestudies.Diabetesisgenerallyassociatedwithcomplicationsandpeoplewithdiabetesusuallytakedifferentmedicationsandmayalreadyhaveanaemiasecondarytorenalimpairment,B12deficiency.Asfortherecipientsafety,abloodfromapersonwithhyperglycaemiabutotherwisehealthyi.e.satisfyblooddonationsafetystandards(norecordofHIV,HepatitisBorC)wouldbequitesafetoreceiveastheextraglucosewouldsimplyberegulatedandutilisedbytherecipient'sbody.Hypoglycemiaisasbadashyperglycemiaandcouldbefatalandhence,generally,itisnotdesiredthatdiabeticsgiveblooddonations.Diabeticpatientstakingbovineorporcineinsulinmaydevelopantibodiesanditisnotrecommendedthattheantibodycontaminatedbloodtobegiventoanyotherperson.Apersonwithhypertensioncandonateblood,aslongasthebloodpressureisnormalatthetimeofblooddonationandthere’snofluctuation.Malariaisalsoreadilytransmittedbybloodtransfusionthroughdonationscollectedfromasymptomatic,parasitaemicdonors.Theparasiteisreleasedintothebloodstreamduringitslifecycleandwill,therefore,bepresentinblooddonatedbyinfectedindividuals.Thepresenceoftotalanti-Plasmodiumspp.antibodiesinthebloodstreamofindividualsmanyyearsafterexposure,withnohistoryofmalariainthemeantime,isimportanttohighlight.Regardingdonorswithcancerblooddonationsshouldnotbetakenfrompeoplewithrecentlyactivemalignancies,exceptinthecaseofbasalcellcarcinomaorcervicalcarcinomainsitu